Why are cytology slides always scanned at low (100X) magnification?

Cytology slides are typically scanned at low magnification, such as 100X, primarily to see if the slide is adequately stained and to identify areas of high cellular concentration. At this magnification, the observer can quickly evaluate the overall quality of the specimen and staining, which are crucial for accurate assessment. It allows for a broader view of the slide, where one can determine if there are regions with increased cellularity that might warrant closer inspection at higher magnifications.

This initial scan helps in locating areas of interest, such as clumps of abnormal cells or areas that require more detailed examination, which can then be observed at higher magnifications. Therefore, this process is foundational in cytological evaluations, ensuring that the most relevant areas are focused on for further analysis.