Which cytology technique helps to minimize cellular damage during sample collection?

Swabbing is the technique that helps to minimize cellular damage during sample collection. This method involves using a soft, moistened material to collect cells from a surface, which reduces the risk of tearing or damaging delicate cells. The gentle contact allows for a more intact cellular layer to be obtained, which is particularly important for preserving the morphology and integrity of the cells for accurate analysis.

In contrast, other techniques may apply more pressure or friction, potentially causing disruption to the cellular structure. For instance, smearing typically involves spreading the sample across a slide, which can lead to cellular distortion if the cells are not handled delicately. Pressing may involve applying a force that could result in cellular rupture, and focusing is not a collection method but rather a technique related to microscopy. By using swabbing, the likelihood of obtaining a clean and viable sample for cytological examination is significantly improved.