What is the main function of neutrophils during inflammation?

Neutrophils play a crucial role in the inflammatory response, primarily through their ability to phagocytize, or engulf and digest, dead tissue and microorganisms. When tissue is injured or infected, neutrophils are among the first immune cells to arrive at the site of inflammation. They act quickly to identify and eliminate pathogens, such as bacteria and fungi, as well as to clear away any damaged cells and debris. This process is vital for initiating tissue repair and restoring homeostasis in the affected area.

Phagocytosis by neutrophils involves recognizing, engulfing, and breaking down these harmful agents, thereby helping to control and resolve the infection. In addition to their phagocytic activity, neutrophils can also release enzymes and reactive oxygen species that further aid in destroying pathogens and can attract additional immune cells to the site of inflammation. This multifaceted action makes neutrophils essential players in the early stages of the immune response during inflammation.