In what time frame should pleural fluid samples ideally be examined after collection?

Pleural fluid samples should be examined immediately after collection to ensure the most accurate diagnosis. The cellular components and biochemical properties of the fluid can change rapidly once the sample is removed from the body due to factors like cell degradation, sedimentation, and changes in pH or biochemical composition. Immediate examination preserves the natural state of the fluid, allowing for better identification of any abnormalities, such as the presence of malignant cells or infectious agents.

Delaying the analysis can lead to erroneous results or the loss of critical cellular details, which can significantly affect clinical decisions and patient management. Therefore, the best practice is to analyze pleural fluid samples as soon as possible after collection.