In cytology, what is often the first step in preparing samples for examination?

Fixing the cells on a slide is a crucial first step in preparing cytological samples for examination. This process involves using a chemical fixative to preserve the cellular structures and morphology. Fixation helps to stabilize the cells and prevents degradation from enzymes or environmental factors, ensuring that the sample accurately represents the cells as they are in vivo. It maintains the integrity of the cell's components, allowing for better visualization and analysis during microscopic examination.

Once the cells are fixed, they can then be subjected to staining, which enhances contrast and highlights specific cell components. However, fixation must occur prior to staining to secure the cellular details needed for an accurate diagnosis. Inspections under a microscope and transportation to a lab are subsequent steps that rely on properly fixed samples. Therefore, fixing the cells is foundational for any further processing or analysis in cytology.